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ProteomicsTMT-based proteomics analysis of arachidonic acid (ARA) treated and control oocytes
Arachidonic acid (ARA) treated and control oocytes in 3 replicates were subjected to the 6-plex TMT labeling, HP-RP fractionation, and LC-MS/MS analysis.
ORGANISM(S): Mus musculus (Mouse) 
2022-02-15 | PXD018753 | Pride
Lc-msms Oocytes Mouse Arachidonic acid Mi 
ProteomicsTMT-based proteomics analysis of GV, GVBD and MII oocytes
Two replicates of GV, GVBD, and MII oocytes were subjected to the 6-plex TMT labeling, HP-RP fractionation, and LC-MS/MS analysis. Two labeling experiments were performed for the total four replicates of each stage of oocytes.
ORGANISM(S): Mus musculus (Mouse) 
2022-02-15 | PXD018777 | Pride
Lc-msms Mii Oocytes Mouse Gvbd Gv 
ProteomicsProteomic analysis of Dpy19l2-deficient human globozoospermia reveals multiple molecular defects
Globozoospermia is a severe teratozoospermia characterized by round-headed spermatozoa without acrosomes, resulting in male infertility. The clinical treatment of globozoospermia involves primarily intracytoplasmic sperm injection because of the low fertilization rate. The deletion of Dpy19l2 is kno...
ORGANISM(S): Homo sapiens (Human) 
2019-08-15 | PXD012302 | Pride
Proteomics Dpy19l2 Human Globozoospermia Round-headed 
ProteomicsTMT-based proteomics analysis of mouse germ cells
The proteome changes were quantified in RibosomeRPL39L-/- spermatocytes and elongated spermatids using TMT 6-plex, and in spermatogonia, spermatocytes, round spermatids and elongated spermatids using TMT 10-plex by LC-MS/MS.
ORGANISM(S): Mus musculus (Mouse) 
2022-10-05 | PXD020874 | Pride
Germ cells Tmt Mouse 
ProteomicsProteomics analysis of 80S ribosomes in nine mouse tissues and different developmental stages of testes
Mass spectrometry data of 80S ribosomes in nine mouse tissues and different developmental stages of testes
ORGANISM(S): Mus musculus (Mouse) 
2022-10-05 | PXD020864 | Pride
Mouse Ribosomes 
ProteomicsDIA-based protein quantification of mouse oocytes from five developmental stages.
The oocytes in 6 replicates from five stages were analyzed using DIA-based protein quantification technology.
ORGANISM(S): Mus musculus (Mouse) 
2025-01-29 | PXD050840 | Pride
Mouse oocytes Dia 
ProteomicsPRM-based quantitative proteomic analysis of ribosomes in GC-1 cell line
Relative protein quantification of RPL4 and RPL39L in non-ribosome, 40S, 60S and ribosome fractions by PRM;Absolute quantification of RPL39 and RPL39L levels in ribosomes of GC-1 wild type cell, and RPL39L-IRES-eGFP-overexpressed RibosomeCore-/Y GC-1 cells with or without dox-induced expression of R...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-19 | PXD037257 | Pride
Gc-1 Protein quantification Ribosome Prm 
ProteomicsSingle-cell proteomics analysis of melatonin-treated and MG132-treated in vitro post-ovulatory aged oocytes
Once ovulated, the oocyte has to be fertilized in a short time window, or it will undergo post-ovulation aging (POA), whose underlying mechanisms are still not elucidated. Here, we optimized single-cell proteomics methods and performed single-cell proteomic and phosphoproteomic analysis of fresh, PO...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD045614 | Pride
Melatonin Oocyte Mouse Proteomics Post-ovulation aging Single cell proteomics Mg132 Phosphorylation 
ProteomicsMulti-omics reveal the metabolic patterns in mouse cumulus cells during oocyte maturation
Bi-directional communication between cumulus cells and the surrounded oocytes is important for the development and functions of both compartments. However, the metabolic framework in cumulus cells has not been systematically described. In the present study, cumulus cells from cumulus-oocyte complex...
ORGANISM(S): Mus Musculus 
2023-03-10 | PXD040796 |
ProteomicsQuantitative proteomics analysis of RPL12 mutant and WT mouse oocytes
RPL12 mutant MII oocytes in 5 replicates and wildtype control in 6 replicates were analyzed using DIA-based protein quantification technology.
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD050652 | Pride
Quantitative proteomics Mouse Rpl12 Dia Oocyte 
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