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We studied the composition of the protein corona formed on 60 nm silver nanoparticles with citrate coating interacted with the human blood plasma under various pH and temperature conditions. The protein corona was analyzed using LC-MS and label-free quantitation.
ORGANISM(S): Homo sapiens (Human) 
2019-01-23 | PXD007648 | Pride
SuperQuant is a quantitative proteomics data processing workflow that utilizes fragment ion complementarity to identify multiple co-isolated peptides in tandem mass spectra. Parent ion and label-free quantification method are supported. The performance of the developed approach was tested using dime...
ORGANISM(S): Homo sapiens (Human) 
2015-05-26 | PXD001907 | Pride
Silver nanoparticles (AgNP) have been reported to penetrate the central nervous system and induce neurotoxicity. However, there is paucity in understanding the toxicity of AgNPs and their effect on the blood-brain barrier (BBB) including the underlying molecular mechanism(s) of action. Using an in v...
ORGANISM(S): Homo sapiens (Human) 
2018-11-07 | PXD009197 | Pride
Protein content of Apis melifera drone male accessory glands (cornua, bulbus and seminal vesicle) investigated by high resolution MS
ORGANISM(S): Apis mellifera (Honeybee) 
2015-05-12 | PXD001993 | Pride
Glucose-dependent insulinotropic polypeptide (GIP) has been proposed to exert insulin-independent effects on lipid and bone metabolism. We investigated the effect of a 6-day s.c. GIP infusion on circulating lipids, white adipose tissue (WAT), brown adipose tissue (BAT), hepatic fat content, and infl...
ORGANISM(S): Homo sapiens (Human) 
2022-11-08 | PXD034803 | Pride
Three glioblastoma subpopulations were analyzed by quantitative proteomics, using dimethyl labeling approach. Deconvolution of mixture spectra using SuperQuant software was employed to increase the depth of quantification.
ORGANISM(S): Homo sapiens (Human) 
2018-03-08 | PXD005245 | Pride
The change in pH of the mobile phase drastically changes the retention mechanism of peptides, rendering currently available retention time prediction models useless. The aim of this study is to create a dataset of peptide retention times under basic (pH 9) HPLC conditions, allowing for the creation ...
ORGANISM(S): Homo sapiens (Human) 
2026-02-13 | PXD064311 | Pride
In this study, we compared the effects of silver and platinum NPs on the main components of the blood brain barrier model: human cerebral microvascular endothelial cells (hCMEM/D3) and human primary astrocytes under single and co-exposure NP conditions. The co-exposure to two types of NPs synergisti...
ORGANISM(S): Homo sapiens (Human) 
2022-11-08 | PXD014425 | Pride
abundance based on normlized TMT, Interaction consistency score: 8.2, Coverage: 45
ORGANISM(S): 100226 
2018-00-00 | 3141927513 | PAXDB
abundance based on Spectral counting, Interaction consistency score: 11.4, Coverage: 45
ORGANISM(S): 100226 
2018-00-00 | 3401610947 | PAXDB
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