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TranscriptomicsSingle-cell RNA and B cell receptor profiling of B cell response to SARS-CoV-2 vaccination
We generated single-cell transcriptomic and BCR sequencing data of B cells from peripheral blood samples taken from a SARS-CoV-2-antigen-naive cohort being vaccinated with the SARS-CoV-2 mRNA-1273 vaccine. Blood samples were collected at the baseline timepoint D-1 (i.e. one day prior to the initial ...
ORGANISM(S): Homo sapiens 
2026-05-08 | E-MTAB-16531 | biostudies-arrayexpress
UnknownThe complete chloroplast genome of Epimedium qingchengshanense G. Y. Zhong et B. L. Guo (Berberidaceae), an endangered species endemic to China.
Not available
S-EPMC7748797 | biostudies-literature
TranscriptomicsMouse Marginal Zone B-cell with/without Tfh RNASeq data analysis
Mouse Marginal Zone B-cell with/without Tfh
ORGANISM(S): Mus musculus 
2024-01-24 | E-MTAB-11677 | biostudies-arrayexpress
TranscriptomicsSmall tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C
Small, non-coding RNAs control gene expression post-transcriptionally and play important roles in virus-host interactions. Within the liver, the microRNA (miRNA) miR-122 is essential for replication of hepatitis C virus (HCV), while repression of miR-148a by hepatitis B virus (HBV) may enhance tumor...
ORGANISM(S): Homo sapiens 
2014-12-18 | E-GEOD-57381 | biostudies-arrayexpress
TranscriptomicsRNAseq of human B-ALL cell lines following RUNX1 or CBFb knock-down
Five B-ALL cell lines representing major genetic subtypes were transfected with shRNAs targeting components of the core binding factor (CBF) complex. Five days after transfection, viable, shRNA-expressing cells were sorted and RNA was harvested. RNAseq was performed and knock-down samples compared t...
ORGANISM(S): Homo sapiens 
2022-04-10 | E-MTAB-10329 | biostudies-arrayexpress
UnknownThe complete chloroplast genome of Epimedium enshiense B. L. Guo et Hsiao (Berberidaceae).
Not available
S-EPMC7782069 | biostudies-literature
ProteomicsMercury intoxication disrupts tonic signaling in B cells, and may promote autoimmunity due to abnormal phosphorylation of STIM-1 and other autoimmunity risk associated phosphoproteins involved in BCR signaling
Epidemiological studies link exposure to mercury with autoimmune disease. Unfortunately, in spite of considerable effort, no generally accepted mechanistic understanding of how mercury actually functions with respect to the etiology of autoimmune disease is currently available. Nevertheless, autoi...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-17 | PXD042189 | Pride
Mercury Phosphorylation Autoimmunity Phospho-serine B cells Bcr Immunotoxicity Stim1 
ProteomicsCharacterization of Primary Patient B-cells under Various Stimulation Conditions
The goal of this project was to compare the effects of differential stimulation of primary patient B-cells with CD40L, CpG, anti-IgM, and IL4 individually and in combination. Additionally, we observed a phenomenon where anti-IgM+CpG treatment resulted in a lymphoma-like phenotype and sought to compa...
ORGANISM(S): Homo sapiens (Human) 
2025-08-21 | PXD016961 | Pride
Human Igm B-cells Ms3 Tmt Immunology Cd40l Hbl-1 Sps-ms3 Cpg Il4 11-plex 
UnknownNF- κ B/HDAC1/SREBP1c pathway mediates the inflammation signal in progression of hepatic steatosis.
Not available
S-EPMC7276689 | biostudies-literature
TranscriptomicsTranscriptome adaptation of group B Streptococcus to growth in human amniotic fluid
We have discovered that GBS significantly remodels its transcriptome in response to exposure to human amniotic fluid. A large number of the affected genes are of unknown function, which means that much remains to be learned about the full influence of amniotic fluid on GBS. The majority of the obse...
ORGANISM(S): Streptococcus agalactiae 
2010-05-18 | E-GEOD-14456 | biostudies-arrayexpress
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