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UnknownDissection of the IgE and T-cell recognition of the major group 5 grass pollen allergen Phl p 5.
Not available
S-EPMC6624141 | biostudies-literature
ProteomicsCDC14B interactome - The proteomic approach aimed at the identification of interaction partners for the human dual phosphatase and tumor suppressor CDC14B by Co-inmunoprecipitation (Co-IP) experiments. In this approach, CDC14B interactomes from unsynchronized and G2/M enriched cells were compared semi-quantitatively based on spectral counting. This approach yielded the deubiquitylase USP9X as a G2/M-specific CDC14B interactor which has been confirmed by Western-blot (WB).
The proteomic approach aimed at the identification of interaction partners for the human dual phosphatase and tumor suppressor CDC14B by Co-inmunoprecipitation (Co-IP) experiments. In this approach, CDC14B interactomes from unsynchronized and G2/M enriched cells were compared semi-quantitatively bas...
ORGANISM(S): Homo sapiens (Human) 
2020-03-25 | PXD012732 | Pride
Usp9x Cdc14b 
ProteomicsA synthetically methylotrophic Escherichia coli as a chassis for bioproduction
Proteome characterization of three E. coli strains: a methanol-dependent strain (MEvo1-0) and two synthetically methylotrophic strains (MEcoli_ref_1, MEcoli_ref_2)
ORGANISM(S): Escherichia coli 
2024-02-08 | PXD046243 | Pride
Synthetic biology Metabolic engineering Synthetic methylotrophy Biotechnology E. coli 
ProteomicsAATF/Che-1 binds ribosome-associated RNAs and regulates ribosome biogenesis
AATF is a predominantly nuclear protein that has been shown to be an apoptosis-inhibiting factor essential for both embryonic development and tumor growth. Several studies have shown a role of AATF in the modulation of pivotal cellular signal transduction pathways such as p53-, mTOR- and HIF-signali...
ORGANISM(S): Homo sapiens (Human) 
2019-08-13 | PXD011055 | Pride
Aatf 
ProteomicsReconstitution of mammalian Cleavage Factor II
Cleavage factor II (CF II) is a poorly characterized component of the multi-protein complex catalyzing 3' cleavage and polyadenylation of mammalian mRNA precursors. We have reconstituted CF II as a heterodimer of hPcf11 and hClp1. The heterodimer is active in partially reconstituted cleavage reactio...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD010177 | Pride
Human Rna processing Dsbu 
ProteomicsStructural and functional characterization of the IgSF21-Neurexin2α complex and its related signaling pathways in the regulation of inhibitory synapse organization
The prevailing model behind synapse development and specificity is that a multitude of adhesion molecules engage in transsynaptic interactions to induce pre- and post-synaptic assembly. How these extracellular interactions translate into intracellular signal transduction for synaptic assembly remain...
ORGANISM(S): Mus musculus (Mouse) 
2024-03-04 | PXD048927 | Pride
C-jun n-terminal kinase Gabaergic synapse Src kinase Camkii kinase Neurexin2α Signal transduction Igsf21 Neuroligin2 
UnknownMeprin β Modulates Brevican Proteolysis Impairing Neural Plasticity and Memory Formation.
Not available
S-EPMC12093287 | biostudies-literature
ProteomicsNAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome
Metabolic dysfunction is a primary feature of Werner syndrome (WS), a human premature aging disease caused by mutations in the gene encoding the Werner (WRN) DNA helicase. WS patients exhibit severe metabolic phenotypes, but the underlying mechanisms are not understood, and whether the metabolic def...
ORGANISM(S): Caenorhabditis elegans 
2020-01-13 | PXD015644 | Pride
Mitophagy Wrn Nad+ Nmnat1 Aging 
ProteomicsThe phosphoproteome of the coral model system Aiptasia
The endosymbiotic interaction established by cnidarians and photosynthetic dinoflagellate algae is the foundation of coral reef ecosystems. This essential interaction is globally threatened to breakdown by anthropogenic disturbance. As such, it is compelling to understand the molecular mechanisms un...
ORGANISM(S): Exaiptasia pallida 
2019-11-06 | PXD014076 | Pride
Aiptasia Cnidarian Coral-model Spectral library Dia/swath-ms Dda Quantification 
UnknownTranscriptomic Analysis of Intestinal Tissues from Two 90-Day Feeding Studies in Rats Using Genetically Modified MON810 Maize Varieties.
Not available
S-EPMC5742243 | biostudies-literature
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