Sort   by:  
 Page size 
ProteomicsTMEM260 is a protein-specific O-mannosyltransferase
Mutations in the TMEM260 gene cause structural heart defects and renal anomalies syndrome (SHDRA), but the function of the encoded protein remains unknown. We report that TMEM260 is an ER-located protein O-mannosyltransferase that selectively glycosylates defined extracellular immunoglobulin, plexin...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2023-05-05 | PXD032328 | Pride
O-mannosylation Glycoproteomics Glycopeptide Tmem260 
ProteomicsMap of the Neuronal Tissue O-glycoproteome Reveal Specific Traits in the Secretogranin Family
Protein O-glycosylation is an abundant PTM of the central nervous system and impairments in O-glycosylation cause severe developmental disorders most with prominent neurological involvement. Despite recent advancements, lack of insight into targets of protein O-glycosylation in neuronal tissues seve...
ORGANISM(S): Homo sapiens (Human) 
2025-07-28 | PXD058040 | Pride
Neurotransmitter Granin Central nervous system Glycosaminoglycans O-glycosylation Cdg Neuroplasticity Dense core granules Domaine Pnn 
ProteomicsDisplay of the Human Mucinome with Defined O-Glycans by Gene Engineered Cells
Mucins are a large family of heavily O-glycosylated proteins that cover all mucosal surfaces and constitute the major macromolecules in most body fluids. Mucins can form aggregated networks and bundles that serve as a barrier, but also assist in containing, feeding, clearing and replenishing microor...
ORGANISM(S): Homo sapiens (Human) 
2021-05-11 | PXD024851 | Pride
Glycosylation Orbitrap Intact mass Mucin 
ProteomicsInstallation of O-glycan sulfation capacities in human HEK293 cells
The human genome contains at least 35 genes that encode Golgi sulfotransferases functioning in the secretory pathway, where they are involved in decorating glycosaminoglycans, glycolipids, and glycoproteins with sulfate groups. Our insight into the sulfotransferases that serve glycoproteins and in p...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD028982 | Pride
Muc1 Sulfated-t Glycosylation Sulfation Sulfated-tn O-glycans 
ProteomicsMap of the Neuronal Tissue O-glycoproteome Reveal Specific Traits in the Secretogranin Family
Impairments in protein glycosylation cause severe developmental disorders and most with prominent neurological involvement. This includes the most abundant GalNAc-type O-glycosylation, but unravelling underlying disease etiologies caused by deficiencies in this glycosylation pathway is hampered by l...
ORGANISM(S): Homo sapiens (Human) 
2025-07-28 | PXD057996 | Pride
Glycosylation Neurotransmitter Granin Mucin Neuron Perineuronal net (pnn) Glycosaminoglycans Central nervous system (cns) Neuroplasticity Dense core granules (dcg) 
ProteomicsNε- and O-Acetylation in Mycobacterium tuberculosis Lineage 7 is Biased Towards Proteins Involved in Growth, Virulence and Antimicrobial Resistance
Protein acetylation is one of the post-translational modifications (PTMs) involved in regulating a myriad of cellular processes in bacteria. Increasing evidence demonstrates that lysine acetylation is involved in Mycobacterium tuberculosis (Mtb) virulence and pathogenesis. However, previous reports ...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2018-05-02 | PXD006630 | Pride
Mycobacterium tuberculosis  lineage 7  post-translational modifications  acetylome  nε-acetylation  o-acetylation. 
UnknownAn atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles.
Not available
S-EPMC7441158 | biostudies-literature
ProteomicsGALNT11 Controlled O-glycans Modulate Ligand Interactions of the Endocytic Receptor LRP1
Low-density lipoprotein receptor (LDLR) and LDLR-related proteins (LRPs) are essential endocytic receptors and regulators of multiple physiological processes including protein reabsorption, cholesterol clearance, and neuronal protein trafficking. Previously, we identified O-GalNAc glycans within lig...
ORGANISM(S): Homo sapiens (Human) 
2026-03-02 | PXD058370 | Pride
Glycosylation Lrp1 Tmt Mass spectrometry Galnt11 
TranscriptomicsIdentification of Gene Products Involved in the Oxidative Stress Response of Moraxella catarrhalis: Evaluation of OxyR dependent Genes
Series of DNA microarrays (4) comparing the M. catarrhalis strain 035E and M. catarrhalis oxyR mutant response to 50 mM hydrogen peroxide. Wild-type cells and oxyR mutant cells were exposed to 50 mM hydrogen peroxide for 15 minutes. RNA was extracted and DNA microarray analysis performed. 4 biologic...
ORGANISM(S): Moraxella catarrhalis 
2010-12-07 | E-GEOD-24351 | biostudies-arrayexpress
UnknownNε- and O-Acetylation in Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains: Proteins Involved in Bioenergetics, Virulence, and Antimicrobial Resistance Are Acetylated.
Not available
S-EPMC5669810 | biostudies-literature
Sort   by:  
 Page size