Sort   by:  
 Page size 
ProteomicsFast open modification spectral library searching through approximate nearest neighbor indexing
Open modification searching (OMS) is a powerful search strategy that identifies peptides carrying any type of modification by allowing a modified spectrum to match against its unmodified variant by using a very wide precursor mass window. A drawback of this strategy, however, is that it leads to a l...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2021-05-25 | PXD009861 | Pride
Ptm Open modification searching Spectral library 
ProteomicsExtremely fast and accurate open modification spectral library searching of high-resolution mass spectra using feature hashing and graphics processing units
Open modification searching (OMS) is a powerful search strategy to identify peptides with any type of modification. OMS works by using a very wide precursor mass window to allow modified spectra to match against their unmodified variants, after which the modification types can be inferred from the c...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2019-12-06 | PXD013641 | Pride
Proteomics Graphics processing unit Post-translational modification Mass spectrometry Feature hashing Approximate nearest neighbor indexing Spectral library Open modification searching 
ProteomicsOpen database searching enables the identification and comparison of glycoproteomes without defining glycan compositions prior to searching
Mass spectrometry has become an indispensable tool for the characterisation of glycosylation across biological systems. Our ability to generate rich fragmentation data of glycopeptides has dramatically improved over the last decade yet our informatic approaches still lag be hide. This is especially ...
ORGANISM(S): Campylobacter fetus subsp. fetus Burkholderia cenocepacia J2315 Burkholderia pseudomallei (strain K96243) Acinetobacter baumannii 
2020-06-24 | PXD018587 | Pride
Wide tolerant database searching Bacterial glycosylation Open searching Glycosylation Glycopeptides Post-translational modifications Proteomics Atypical glycosylation 
UnknownFast Open Modification Spectral Library Searching through Approximate Nearest Neighbor Indexing.
Not available
S-EPMC6173621 | biostudies-literature
UnknownAccelerating open modification spectral library searching on tensor core in high-dimensional space.
Not available
S-EPMC10323168 | biostudies-literature
UnknownOpen Modification Searching of SARS-CoV-2-Human Protein Interaction Data Reveals Novel Viral Modification Sites.
Not available
S-EPMC9554009 | biostudies-literature
ProteomicsThe application of open searching based approaches for the identification of Acinetobacter baumannii O-linked glycopeptides decorated with diverse capsule derived glycans
Protein glycosylation is being increasingly recognised as a common modification within microbial organisms, contributing to protein functionality and optimal infectivity of pathogenic species. Due to this, the interest in characterising microbial glycosylation events is increasing - requiring high-t...
ORGANISM(S): Acinetobacter baumannii ACICU Acinetobacter baumannii AB307-0294 Acinetobacter baumannii D1279779 
2021-11-02 | PXD027820 | Pride
Lc-ms Proteomics Glycopeptides 
UnknownExtremely Fast and Accurate Open Modification Spectral Library Searching of High-Resolution Mass Spectra Using Feature Hashing and Graphics Processing Units.
Not available
S-EPMC6886738 | biostudies-literature
ProteomicsAccelerating Open Modification Spectral Library Searching on Tensor Core in Hyperdimensional Space
HOMS-TC is an open modification spectral library search (OMS) tool for mass spectrometry-based proteomics. Our tool redesigns the MS/MS spectral matching algorithm based on hyperdimensional computing (HDC) and accelerates OMS on GPU in an end-to-end manner.
ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast) ncbitaxon:4932 Homo Sapiens (human) ncbitaxon:9606 
2023-02-02 | MSV000091183 | MassIVE
ProteomicsDiscovery and visualization of uncharacterized drug-protein adducts using mass spectrometry
Drugs are often metabolized to reactive intermediates that form protein adducts. Adducts can inhibit protein activity, elicit immune responses, and cause life threatening adverse drug reactions. The masses of reactive metabolites are frequently unknown, rendering traditional mass spectrometry-based ...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2022-02-24 | PXD025019 | Pride
Magnum Raloxifene Dicloxacillin Adduct Plasma Cyp3a4 Open search Metamorpheus Comet Human serum albumin Msfragger Penicillin Moda Hsa Xenobiotic Reactive metabolite P450-reductase Flucloxacillin Open-pfind Comet-ptm Limelight 
Sort   by:  
 Page size