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PML nuclear body (PML NB) recruits different client proteins under different cell context. We used TurboID proximity labeling (PL) method followed by MS to determine the composition of PML NBs in mESCs, differentiated cells, and NaAsO2-treated mESCs.
ORGANISM(S): Mus musculus (Mouse) 
2023-01-10 | PXD037432 | Pride
Oral squamous cell carcinoma (OSCC) is a prevalent type of head and neck cancer, accounting for more than 90% of all oral malignancies worldwide. The identification of diagnostic and prognostic markers for OSCC is crucial for improving patient outcomes, as early detection and treatment are critical ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD048046 | Pride
Biotin identification (BioID) is a proximity-dependent labeling technique to study protein-protein co-localization in vivo. Although BioID has been applied in animal cells, plants and yeast, the method remained to be established in filamentous fungi. In this study, we established BioID for the filam...
ORGANISM(S): Sordaria macrospora 
2022-10-25 | PXD034217 | Pride
BRD9 was identified in a genome-wide screen for genes regulating the response to interferon (IFN) in a A549 based reporter cell line. Subsequent experiments determined an involvement of BRD9 in the transcriptional regulation of Interferon-stimulated genes (ISGs) expression following stimulation with...
ORGANISM(S): Homo sapiens (Human) 
2021-08-17 | PXD026926 | Pride
The synchronization of the internal circadian clock with the external 24-h diurnal cycle is critical for ensuring optimal plant growth fitness. Despite lacking a DNA binding domain, LIGHT-REGULATED WD proteins (LWDs) are essential for sustaining and fine-tuning circadian rhythm1,2. However, the acti...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2026-07-21 | PXD062258 | Pride
Here we are using unbiased proteomic analysis based on proximity labelling and TurboID coupled to MS to try to identify specific interactors of AURKB and ACP1 in GBM43 human glioblastoma cells.
ORGANISM(S): Homo sapiens (Human) 
2026-05-18 | PXD077507 | Pride
It is documented that intracellular succinate levels are maintained and regulated by mitochondrial complexes II. In order to define the LONP1-dependent regulators of succinate content, unbiased TurboID-based proximity labeling was employed to exploit LONP1-targeting proteins. Our results showed that...
ORGANISM(S): Homo sapiens (Human) 
2023-04-08 | PXD031197 | Pride
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