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ProteomicsMS-based identification of AcP10 interaction partners.
In times of cellular stress, such as during virus infections, the integrated stress response (ISR) blocks translation initiation through phosphorylation of the essential translation initiation factor eIF2. Phosphorylated eIF2 (p-eIF2) sequesters the eIF2-specific guanidine exchange factor (GEF) eIF2...
ORGANISM(S): Homo sapiens (Human) 
2020-07-24 | PXD011879 | Pride
Ap-ms Eif2 Bw10 Interactome Eif2b 
ProteomicsStreamlined isolation of the n-terminome
SIMPATICO is a streamlined N-termini proteome workflow which leverages NHS ester chemistry. At the protein level, N-terminal amines (naturally occurring protein N-termini, lysines, or protease-generated N-termini) are blocked directly in the cell lysate, and tryptic digestion is performed straight a...
ORGANISM(S): Homo sapiens (Human) 
2026-09-03 | PXD064097 | Pride
Tmt Lfq Proteolysis N-terminome Degradomics 
ProteomicsQuantitative proteomics profiling of protein kinase A substrates - Jurkat clone E6.1
Here we evaluate and explore a peptide-centric antibody generated to selectively enrich peptides containing the cAMP-dependent protein kinase A (PKA) consensus motif. This targeted phospho-proteomic strategy is used to profile temporal quantitative changes of protein PKA substrates in Jurkat T-lymph...
ORGANISM(S): Homo sapiens (Human) 
2013-07-25 | PXD000148 | Pride
Targeted approach Dimethyl lableing Immunoprecipiation Phosphoproteomics Lc-msms 
UnknownThe Drosophila RZZ complex - roles in membrane trafficking and cytokinesis.
Not available
S-EPMC3482314 | biostudies-literature
ProteomicsSecretome analysis of primary CLL cells
Secretome analysis of primary CLL cells co-cultured in serum-free IMDM medium with either EL08 stroma cells or YK6 follicular dendritic cells overexpressing CD40L and interleukin 21 (“FDC CD40L IL21”).
ORGANISM(S): Homo sapiens (Human) 
2026-01-22 | PXD069904 | Pride
Leukemia Dia Proteomics Secretome 
ProteomicsIdentification of targetable T-cell antigens in multiple myeloma
We applied a mass spectrometry-based immunopeptidomics approach on primary multiple myeloma (MM) samples and MM cell lines, integrating whole-exome and RNA sequencing to comprehensively characterize the MM immunopeptidome and systematically search for TAAs and neoantigens.
ORGANISM(S): Homo sapiens (Human) 
2026-07-23 | PXD072525 | Pride
Hla Proteomic Multiple myeloma Proteogenomic 
ProteomicsN-terminomics on WT and CASP2 KO mouse hearts
To identify putative substrates processed by Caspase-2 in response to PIDDosome activation in cardiomyocytes, we performed N-terminomics by TMT10-TAILS on P7 hearts isolated from XMLC2-Casp2fl/fl and XMLC2+Casp2fl/fl mice.
ORGANISM(S): Mus musculus (Mouse) 
2026-01-15 | PXD060421 | Pride
Tmt-tails Caspase 2 Heart developement N-terminomics 
ProteomicsMast cells modulate macrophage through release of Csf1
To systematically identify mast cells-released mediators, we analysed the proteome and secretome of antigen-activated primary mouse mast cells using quantitative mass spectrometry-based proteomics and identified Csf1 as a novel preformed mast cell mediator.
ORGANISM(S): Mus musculus (Mouse) 
2025-06-23 | PXD050282 | Pride
Mast cell proteome Macrophage differentiation Macrophage polarisation Secretome 
ProteomicsBCMA ubiquitylation in multiple myeloma
Mass spectrometric analysis of MM cell-purified B-cell maturation antigen (BCMA) protein to identify ubiquitylation sites.
ORGANISM(S): Homo sapiens (Human) 
2025-07-29 | PXD056372 | Pride
Ubiquitylation Bcma Di-glycine Ubiquitin 
ProteomicsMouse liver proteome in Germ-free, Specific pathogen free, and OMM12 colonizes mice
Bile acids (BA) are synthesized in the liver before excretion into the bile. Consequently, to clarify how the gut microbiota increases biliary TCA and TMCA contents, hepatic BA metabolism was investigated by analyzing the liver proteome of GF, OMM12 and SPF mice.
ORGANISM(S): Mus musculus (Mouse) 
2026-07-30 | PXD060110 | Pride
Mouse Tmt Liver Proteome 
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